STAGE 4 MEANS THE TRANSITION OF THE DISEASE FROM THE EXTRACELLULAR MATRIX TO SPECIALISED ORGAN CELLS WITH CONCURENT MORE SERIOUS DIAGNOSIS OF ORGAN DAMAGE.

Diagnoses that fall into this stage are migraine, eye twitching, viral infections, asthma, ulcers, toxic liver damage, nephrotic syndrome, autoimmune glomerulonephritis, chronic arthritis, benign prostate hyperplasia, bronchitis, angina pectoris, myocarditis, and many others.

The treatment strategy in this phase is more complex, and at the beginning, it is necessary to support the cellular processes. It is imperative to start with boosting the cellular energy mechanisms with orthomolecular therapy, ion induction therapy, hyperthermia, boosting the catalysts of the citric acid cycle, coenzyme Q10, alpha lipoic acid, vitamin C, specific herbs, and many, many others. In this way, we give the cells the energy they need to excrete disturbing agents into the extracellular matrix and maintain organ function. Since the extracellular matrix is now the “dumping ground”, we need to concurrently activate the drainage of the extracellular matrix itself and all the excretory organs, namely the liver, kidneys, skin, intestinal mucosa through again orthomolecular remedies, herbs, special herbal tonics and oils, and specific therapies. We must not forget to neutralize reactive oxygen species. In a way, it is about triggering an effective stage 2 that is able to remove the disturbing noxious agents from the body. In the clinic, we support this with neural therapy, ozone, cupping, many of the Ayurvedic techniques, and others. Increasing the membrane potential is achieved through ion-induction therapy with Papimi and Indiba accompanied by minerals, essential fatty acids, etc. Pharmaceuticals are used with the awareness that suppression is not desirable at this stage. On the other hand, we have to be extremely strict about oral health at this stage because many of the root causes could originate in the mouth, such as infectious inflammation of the bone and soft tissues (periodontitis, “granuloma”—dead teeth), non-infectious FDOJ, or in older days, NICO, materials (metals and plastics), and also the effects of the bite on postural problems. In the end, of course, more rigor in diet, hydration, etc.

So we observe direct effects on cellular functions, e.g., enzymes, but also on cell membranes and mitochondria. As Reckeweg wrote, at this stage, we are usually presented with a patient who has some form of chronic inflammation. Basically, the inflammation is going on in an extracellular matrix, which, because of its chronicity, leaves damaging after-effects. The whole biochemical imbalance accumulates around organ parenchyma, and the inflammation is just a stage 2 reaction that tries to isolate the noxious situation by “scarring” it. Ultimately, this process damages the organ itself. If the ongoing defense is not treated and detoxification is not initiated, degeneration of the organ structures is inevitable.