Stage 6

Dedifferentiation stage 6 is the last stage in which cells genetic material is damaged and new growth (cancer) has emerged.


If patients still don't act with the correct integrative medicine strategy, the buildup of noxious agents, aka "garbage" damages the cell`s genetic material and severely affects cellular respiratory mechanisms.

OXIDATIVE-FREE RADICALS CONTINUE TO DAMAGE ORGANS AND INCREASE THEIR DYSFUNCTION AND TISSUE DEGENERATION. CELLULAR RESPIRATION IS NO LONGER OXIDATIVE, BUT IT CHANGES TO FERMENTATION, i.e., WARBURG EFFECT.

Diagnoses that fall into this group are basically all forms of cancer. Especially in this stage, we work together with our good partner clinic from Switzerland, Biomedicine Sonnenberg which has plenty of experience in the integrative oncology field, and together we have great success.

INTEGRATIVE ONCOLOGY CANCER TREATMENT STRATEGIES

Logically, therapies in this stage must be carefully planned, and besides all of the explanations in the first five stages, in stage 6, strictness in the removal of chronic foci is mandatory. This includes periodontal disease, “dead” teeth, metals in the mouth, and any scars in the body. Working the gut microbiome is of the essence since 80% of the immune system grows in the walls of the intestines. Integrative oncology offers a series of direct antitumor substances and specific blood tests for testing the effectiveness of chemotherapy agents and integrative medicine anticancer agents in order to make treatment as effective as possible. All the other strategies are in essence the same as in previous phases since the body still needs to unload the accumulated toxic burden.

This stage is a final consequence of failed control of the accumulation of exogenous and endogenous noxious agents. Free radicals continue to promote organ dysfunction and tissue degeneration. Cellular metabolism is no longer oxidative phosphorylation, but it changes to “fermentation”, which means “breathing” on a cellular level. The dedifferentiated cells are then released into blood circulation. In general, at this stage, we must be aware that the organism has severely reduced its energy reserves and its regulatory capacity.


Stage 5

The degeneration stage is marked by deeper intracellular noxious agents which is accompanied by reduced cell function.


Cells are by now severely damaged, restoration of the cell's membrane, enzymes, other proteins, and genetic material is crucial.

WE ARE GETTING DEEPER AND DEEPER. ORGAN STRUCTURE WITH ITS FUNCTION IS INCREASINGLY AND IRREVERSIBLY DAMAGED. RESTORATION OF CELL’S MEMBRANE, ENZYMES, OTHER PROTEIN, AND GENETIC MATERIAL IS CRUCIAL TO PREVENT TRANSITION TO THE NEXT MOST UNWANTED STAGE 6.

If there is still no therapeutically planned detoxification with drainage in combination with upbuilding treatment done and only suppressive medication is employed, then organ structure and its function are increasingly and irreversibly damaged.

Typical diagnoses in phase 5 are dermatoses including psoriasis, periodontal disease, Atrophic rhinitis, Parkinson’s’ disease, Alzheimer’s disease, ALS, Macular degeneration, glaucoma, Addison`s disease, COPD, Chron disease, ulcerative colitis, Hashimoto disease, Scleroderma, Osteoporosis, Arthrosis, Ankylosing spondylitis, Myocardial infarction, etc.

PROTECTIVE AND REPAIRING TREATMENTS FOR CELL’S GENETIC AND NON-GENETIC MATERIAL

Treatment continues with the activation of general bodily defenses to elicit efficacious reactive stage 1 and 2 with neural therapy, homeopathy, herbals, ozone therapy, acupuncture, etc. In targeted antioxidant therapy, as we wrote elsewhere, reactive oxygen species are further produced in this phase. Activation of drainage of organs and extracellular matrix in the microscopic world means draining of cells with specific orthomolecular detoxification, herbal sauna, other medical ayurvedic techniques, colon hydrotherapy or enemas, etc. It is necessary to increase membrane potential since it is lowered with the deepening of the disease process with alkaline minerals like magnesium, potassium, calcium, and also essential fatty acids. Among many therapeutic approaches, Papimi is extremely effective in this case. Again, special attention must be taken to the use of suppressing pharmaceuticals and smartly and carefully adjusting the dosing during the treatments. During treatment, an orthomolecular strategy must be prescribed and planned. As always, the most important part and the part that you, as a patient, have complete control over is taking care of adequate hydration and reducing the dietary antigenic and toxic load.

Continuous degenerative harm is done to the cells with an effect on genetic and other structures like membranes, enzymes, other proteins, etc. Inevitable toxin accumulation continues, which just multiplies with chronic inflammation. It is valid to say that toxins at this stage due to glandular impregnation cause hormonal imbalance and reduced capacity for immunomodulation. In the end, the body’s defenses in terms of inflammation and cells themselves are so suppressed that the proliferation of anomalous cells occurs. At this stage, improvements are possible, but it is fair to say that full recovery MAY not be possible even with an integrative approach. However, with the modern integration of all medical knowledge and long-term treatment, everything is possible. The focus is always on supporting cell function and improving affected regulation. Again, we must not forget proper oral health, as described elsewhere. Cellular support is planned based on diagnostics, with the main aim being increasing ATP energy production through vitamins, herbs, homeopathic and supporting therapies such as Papimi ion therapy local radiofrequency hyperthermia therapy, and many others. In this way, cells get the basics in order to regain their specialized function and ability to excrete metabolism byproducts and toxic load.


Stage 4

Stage 4: causative noxious agents have penetrated into the cells. The treatment strategy must include cellular detoxification.


In this phase, the noxius agents damage the cell membranes, enzymes, etc.

STAGE 4 MEANS THE TRANSITION OF THE DISEASE FROM THE EXTRACELLULAR MATRIX TO SPECIALISED ORGAN CELLS WITH CONCURENT MORE SERIOUS DIAGNOSIS OF ORGAN DAMAGE.

Diagnoses that fall into this stage are migraine, eye twitching, viral infections, asthma, ulcers, toxic liver damage, nephrotic syndrome, autoimmune glomerulonephritis, chronic arthritis, benign prostate hyperplasia, bronchitis, angina pectoris, myocarditis, and many others.

The treatment strategy in this phase is more complex, and at the beginning, it is necessary to support the cellular processes. It is imperative to start with boosting the cellular energy mechanisms with orthomolecular therapy, ion induction therapy, hyperthermia, boosting the catalysts of the citric acid cycle, coenzyme Q10, alpha lipoic acid, vitamin C, specific herbs, and many, many others. In this way, we give the cells the energy they need to excrete disturbing agents into the extracellular matrix and maintain organ function. Since the extracellular matrix is now the “dumping ground”, we need to concurrently activate the drainage of the extracellular matrix itself and all the excretory organs, namely the liver, kidneys, skin, intestinal mucosa through again orthomolecular remedies, herbs, special herbal tonics and oils, and specific therapies. We must not forget to neutralize reactive oxygen species. In a way, it is about triggering an effective stage 2 that is able to remove the disturbing noxious agents from the body. In the clinic, we support this with neural therapy, ozone, cupping, many of the Ayurvedic techniques, and others. Increasing the membrane potential is achieved through ion-induction therapy with Papimi and Indiba accompanied by minerals, essential fatty acids, etc. Pharmaceuticals are used with the awareness that suppression is not desirable at this stage. On the other hand, we have to be extremely strict about oral health at this stage because many of the root causes could originate in the mouth, such as infectious inflammation of the bone and soft tissues (periodontitis, “granuloma”—dead teeth), non-infectious FDOJ, or in older days, NICO, materials (metals and plastics), and also the effects of the bite on postural problems. In the end, of course, more rigor in diet, hydration, etc.

So we observe direct effects on cellular functions, e.g., enzymes, but also on cell membranes and mitochondria. As Reckeweg wrote, at this stage, we are usually presented with a patient who has some form of chronic inflammation. Basically, the inflammation is going on in an extracellular matrix, which, because of its chronicity, leaves damaging after-effects. The whole biochemical imbalance accumulates around organ parenchyma, and the inflammation is just a stage 2 reaction that tries to isolate the noxious situation by “scarring” it. Ultimately, this process damages the organ itself. If the ongoing defense is not treated and detoxification is not initiated, degeneration of the organ structures is inevitable.


Stage 3

Stage 3: The body’s own defense processes cannot manage to completely expel toxins. They are deposited in the extracellular matrix, in adipose tissue, and in the entire vascular system.


At this stage, it is of utmost importance to stimulate cellular metabolism to get rid of deposited material of any origin.

THE DEFENCE MECHANISMS OF STAGES 1 AND 2 MUST BE ACTIVATED DUE TO THE DEPOSITION OF NOXIOUS AGENTS IN THE CONNECTIVE TISSUE. DRAINAGE AND IMMUNE SYSTEM-SPECIFIC TREATMENTS MUST BE ACTIVATED.

Diagnoses at this stage are atheromas, warts, cysts, polyps, neuromas, constipation, cholelithiasis, obesity, gout, edema, lymph gland swelling, prostatic hypertrophy, fibroids, and rheumatism, to name a few.

SPECIFIC CONNECTIVE TISSUE DRAINAGE AND ACTIVATION OF DETOXIFICATION ON A CELLULAR LEVEL

  • Specific drainage remedies
  • Specific Ayurvedic treatments
  • Osteopathic drainage treatments
  • Specific papimi Ion-Induction-Therapy regimen
  • Specific local and systemic hyperthermia
  • IHHT: Intermittent hyper, hypoxic treatment
  • Integrative Dentistry

In general, the first 3 stages can be treated with great success if the therapies are planned appropriately and integratively. It must be remembered that these three stages affect the fluid and the extracellular matrix, and the biochemical mechanisms of the cell are not yet damaged. We must be aware that from the 3rd stage until the next 4th stage, the organism does not have an efficient biological defense and draws energy away from detoxification. The cellular metabolic functions need stimulation from your integrative therapist to recover and support the release and gradual elimination of toxin deposits to maintain energy for the vital organs.

The therapeutic strategies in this phase are similar to those in the previous stage. That is, activating the body’s own drainage through the kidneys, liver, skin, and intestinal mucosa and draining the extracellular matrix through the lymphatic and vascular systems We can achieve this by combining Ayurvedic herbal medicine, orthomolecular therapies with either supplements or infusions or both, medicinal saunas, enemas or intestinal hydrotherapy, cupping, homeopathy, and others. When stage 2 defenses are prolonged over time, we need to be wary of oxidative processes. Based on laboratory results and our experience, high doses of antioxidants are prescribed. Again, dietary review is essential to ensure adequate hydration and reduce the antigenic load of food. The activation of immune cell-producing organs such as bone marrow and thymus is essential. The secondary lymphoid organs must not be forgotten. These organs include the lymph nodes, spleen, tonsils, and certain tissues in various mucosal layers of the body (e.g., Peyer`s patches in the intestine).


Stage 2

Stage 2: Reaction Stage
It is characterized by expelling the noxious agents, which can be of internal or external origin.


In this stage, the body`s natural defenses are activated. The most frequent are vomiting, diarrhea, fever and inflammation

STAGE 2: ACTIVATE THE DEFENSIVE MECHANISMS. SUPPORT THE BODY’S DEFENCES AND TARGET-DIAGNOSED ”NOXIOUS AGENT” WITH SPECIFIC NON-INVASIVE OR INVASIVE THERAPIES.

This group includes dermatitis, erythema, eczema, stomatitis, rhinitis, herpes zoster, poliomyelitis, neuralgia, pharyngitis, laryngitis, colitis, hepatitis, abscess, osteomyelitis, tonsillitis, and polyarthritis, to name a few.

TARGET SPECIFIC CAUSATIVE ”NOXIOUS AGENT” THAT WAS DISCOVERED DURING ANAMNESIS AND DIAGNOSTICS.

  • Chemical substances (glyphosate, PFOA, pesticides, DDT, herbicides)
  • Bacteria (streptococci, staphylococci, borrelia, etc.)—most importantly
  • Viruses (EBV, VZV, CMV, Influeza, COVID-19, etc.)—the most relevant
  • Heavy metals (arsenic, cadmium, lead, mercury, etc.)

The most common defenses are fever, diarrhea, and inflammation, and with them can come troublesome symptoms. In integrative medicine, symptoms are seen as a serious attempt by the body to get back to stage 1 health. Symptoms, though annoying, become valuable signs that the organism is attempting to regulate toward recovery. Only in rare cases does one need medication for fever, pain, and inflammation. More so, overuse of so-called NSAID drugs can progress the disease to deeper stages. In some cases, they are used, and the dosage has to be chosen carefully.

The therapeutic strategies at this stage are to activate the drainage of organs such as the kidneys, liver, skin, and intestinal mucosa, as well as the drainage of the extracellular matrix, as described elsewhere. We can achieve this by combining Ayurvedic herbal medicine, orthomolecular therapies with either supplements or infusions or both, medicinal saunas, enemas or colon hydrotherapy, homeopathy, and others. When inflammation is prolonged, we need to be wary of reactive oxidative species in layman’s terms. We need to watch out for high levels of antioxidants, based on laboratory results and our experience. Again, dietary review is imperative to ensure adequate hydration and reduce the antigenic load of food.


Stage 1

STAGE 1: TAKING CARE OF REGULAR DAILY EXCRETION AND MAINTAINING A HEALTHY STATE.


In this stage, natural bodily detoxification pathways should work normally.

TAKING CARE OF REGULAR DAILY EXCRETION AND MAINTAINING A HEALTHY STATE.

Excretion is a prerequisite for the human body to function normally in daily life. This stage is always addressed with therapies, regardless of the diagnosis. We must ensure that numerous endogenous detoxification mechanisms function normally and intervene at the first signs of internal or external noxious agents that block excretion. The excretory pathways are sweat, sebum, saliva, gastrointestinal secretions, bile, pancreatic juice, menstruation, lymph, urine, menstruation, semen, etc.

Excretion of harmful substances normally occurs through the physiological orifices of the body. For example, vomiting or diarrhea normally only require the replacement of fluids and electrolytes

We normally test the major excretory pathways in the blood, for example, glutathione transferase, superoxide dismutase, cystatin C, and others. Surprisingly, all these detoxification enzymes need to be activated.

YOUR CRUCIAL ROLE:

Since fluids make up the majority of our bodies, it is important that we stay hydrated. Water is the medium in which all biochemical reactions take place, and if there is not enough water, the body`s biochemistry cannot function. It is the same as if you wanted to dissolve a spoonful of salt in a glass of water.

We always advise organic food and locally sourced if possible. Avoid all processed foods, even if they are organic. We often test for elevated levels of glyphosate in the blood. One patient was even positive for DDT. We always advise avoiding cow’s milk products because of the increased levels of beta-lactoglobulin, and all our patients are extremely happy when they do this. We normally advise eating as little gluten as possible and, of course, strictly avoiding sugar.