Stage 1
STAGE 1: TAKING CARE OF REGULAR DAILY EXCRETION AND MAINTAINING A HEALTHY STATE.
In this stage, natural bodily detoxification pathways should work normally.
TAKING CARE OF REGULAR DAILY EXCRETION AND MAINTAINING A HEALTHY STATE.
Excretion is a prerequisite for the human body to function normally in daily life. This stage is always addressed with therapies, regardless of the diagnosis. We must ensure that numerous endogenous detoxification mechanisms function normally and intervene at the first signs of internal or external noxious agents that block excretion. The excretory pathways are sweat, sebum, saliva, gastrointestinal secretions, bile, pancreatic juice, menstruation, lymph, urine, menstruation, semen, etc.
Excretion of harmful substances normally occurs through the physiological orifices of the body. For example, vomiting or diarrhea normally only require the replacement of fluids and electrolytes
We normally test the major excretory pathways in the blood, for example, glutathione transferase, superoxide dismutase, cystatin C, and others. Surprisingly, all these detoxification enzymes need to be activated.
YOUR CRUCIAL ROLE:
Since fluids make up the majority of our bodies, it is important that we stay hydrated. Water is the medium in which all biochemical reactions take place, and if there is not enough water, the body`s biochemistry cannot function. It is the same as if you wanted to dissolve a spoonful of salt in a glass of water.
We always advise organic food and locally sourced if possible. Avoid all processed foods, even if they are organic. We often test for elevated levels of glyphosate in the blood. One patient was even positive for DDT. We always advise avoiding cow’s milk products because of the increased levels of beta-lactoglobulin, and all our patients are extremely happy when they do this. We normally advise eating as little gluten as possible and, of course, strictly avoiding sugar.
Biological dentistry: fundamentals and effective Methods: Preventive measures and therapeutic approaches to promote bone and soft tissue healing.
Biological dentistry: fundamentals and effective Methods: Preventive measures and therapeutic approaches to promote bone and soft tissue healing.
Biological Dentistry is a dynamic field that recognizes the intricate interplay between oral health and systemic well-being. This abstract provides a comprehensive exploration of the core principles and practical applications within Biological Dentistry, highlighting its significance in the context of modern healthcare’s shift towards prioritizing healthspan over mere lifespan.
At the heart of Biological Dentistry lies the profound recognition that oral health is not an isolated concern but an integral component of overall well-being. This understanding begins with a detailed examination of the microbiome and osteoimmunology, two pillars that underpin the biological mechanisms governing oral health.
The oral cavity houses a thriving ecosystem, hosting a diverse community of microorganisms, including over 700 distinct bacterial species, viruses, and fungi. These inhabitants, along with their metabolites and pro-inflammatory mediators, wield a remarkable capacity to exert influence far beyond their immediate domain. Specific attention is devoted to pathogenic microorganisms such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. These bacteria, recognized for their roles not only in causing localized oral conditions but also in driving systemic implications, illustrate the interconnectedness of oral and systemic health. Porphyromonas gingivalis, for instance, has been closely associated with gut dysbiosis and its potential to disrupt the gut microbiome equilibrium. Additionally, the secretion of gingipain by this bacterium has been implicated in the progression of Alzheimer’s disease. Likewise, Aggregatibacter actinomycetemcomitans is examined for its potential to heighten the metastatic potential of pancreatic cancer, thereby highlighting the systemic consequences of oral health. Crucially, the influence of these bacteria often manifests through inflammatory responses, reinforcing the central role of inflammation in both local and systemic pathologies.
Osteoimmunology, a burgeoning field investigating the intricate interaction between the immune system and bone metabolism, assumes critical importance in comprehending the complex relationship between inflammation and bone health. A paradigm shift from viewing bones as static structures to dynamic, continuously remodeling tissues is articulated. The regulatory mechanisms governing this remodeling process, notably RANKL (receptor activator of nuclear factor kappa B ligand) and OPG (osteoprotegerin), which modulate the activity of osteoclasts, are elucidated. Particular emphasis is placed on the influence of bacterial lipopolysaccharides, with Porphyromonas gingivalis as a notable example. These lipopolysaccharides have been shown to upregulate RANKL expression in osteoblasts, ultimately leading to bone loss in periodontal disease.
This exploration underscores the critical need to recognize the intricate connections between oral health, the microbiome, osteoimmunology, and systemic well-being. Such recognition not only underscores the need for a comprehensive approach but also aligns with the evolving paradigm of modern healthcare, which increasingly focuses on healthspan over lifespan. Today’s healthcare system recognizes that longevity alone does not equate to quality of life. Instead, the emphasis is shifting towards enhancing healthspan – the period of life marked by good health and well-being. In this context, Biological Dentistry takes on a pivotal role, as it acknowledges that oral health is an integral element of overall healthspan.
In conclusion, this comprehensive exploration underscores the vital importance of Biological Dentistry within the evolving landscape of modern healthcare. It serves as a compelling argument for healthcare systems to prioritize healthspan, promoting both oral and overall health through a deeper understanding of the connections between oral health, the microbiome, osteoimmunology, and systemic well-being. This paradigm shift represents a crucial step towards enhancing the quality of life for individuals across the lifespan.
Unveiling the Oral Systemic Axis: Exploring the Role of Microbiome and Osteoimmunology in Biological Dentistry
Unveiling the Oral-Systemic Axis: Exploring the Role of Microbiome and Osteoimmunology in Biological Dentistry
Biological Dentistry emerges as a burgeoning field acknowledging the intricate interplay between oral well being and systemic health.
This abstract delves into the indispensable role of the microbiome and osteoimmunology as pivotal elements influencing ove rall systemic health within the domain of dentistry. Within the oral cavity resides a myriad of diverse bacteria, viruses, and fungi, comprising a staggering 700 distinct species. These microorganisms, together with their byproducts and inflammatory mediat ors, have the potential to traverse various pathways, including ingestion via saliva, thereby potentially exerting an impact on other bodily regions.
Research studies have illuminated the significance of specific bacteria, such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, not only in causing localized oral ailments but also in bearing systemic ramifications. Porphyromonas gingivalis has been associated with gut dysbiosis, as it manages to withstand the harshness of stomach acid an d disrupts the equilibrium of the gut microbiome. Additionally, the gingipain secreted by this bacterium has been implicated in the progression of Alzheimer’s disease. Conversely, Aggregatibacter actinomycetemcomitans has been discovered to heighten the me tastatic potential of pancreatic cancer. Rather than directly causing destruction, the inflammatory response triggered by these bacteria contributes to the deterioration of tooth supporting tissues and aggravates systemic inflammation.
Osteoimmunology, th e field that studies the interaction between the immune system and bone metabolism, offers valuable insights into the intricate relationship between inflammation and bone health. Previously viewed as relatively inert, bone is now recognized as a dynamic ti ssue undergoing constant remodeling. This process is governed by diverse factors, including RANKL (receptor activator of nuclear factor kappa B ligand) and OPG (osteoprotegerin), which regulate osteoclast activity. Bacterial lipopolysaccharides, such as th ose emanating from Porphyromonas gingivalis, have been demonstrated to enhance RANKL expression in osteoblasts, leading to bone loss in periodontal disease.
Appreciating these complex connections between oral health, the microbiome, osteoimmunology, and s ystemic health is of paramount significance within the realm of biological dentistry. By acknowledging the influence of oral pathogens and inflammation on systemic well being, a comprehensive approach can be embraced to foster both oral and overall health.
In the pursuit of enhancing osseointegration and implant stability, a pilot study was conducted utilizing a unique Ion Induction Therapy (IIT) protocol, along with IV Ozone. Preliminary results showcased remarkable outcomes, with Osstell ISQ scores avera ging 72 after 16 weeks post op. This data presents a notable advantage over a comparable study by Vladimir Kokovic et al., which achieved an average ISQ value of 64 for the same type of implant. Notably, ISQ scores above 70 indicate high stability, 60 69 s ignify medium stability, and scores below 60 denote low stability. This promising integration of IIT and IV Ozone highlights the potential to elevate osseointegration, thereby underlining the practical impact of these interventions in the realm of biologic al dentistry.
Further exploration through research endeavors and clinical investigations is warranted to advance our comprehension and devise effective strategies in biological dentistry, ultimately enhancing patient outcomes and systemic well being.
Author:
Dr. med. dent. Sebastjan Perko, Phd.
dr.perko@maha.si www.maha.si
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Biological Dentistry is an emerging field that recognizes the interplay between oral health and systemic health.
Biological Dentistry is an emerging field that recognizes the interplay between oral health and systemic health.
Biological Dentistry is an emerging field that recognizes the interplay between oral health and systemic health. This abstract explores the pivotal role of the microbiome and osteoimmunology as key factors influencing overall systemic health in the context of dentistry.
The oral cavity harbors a diverse array of bacteria, viruses, and fungi, with over 700 different species residing in the mouth. These microorganisms, along with their byproducts and inflammatory mediators, can travel through pathways such as saliva ingestion, potentially impacting other parts of the body.
Studies have revealed that certain bacteria, such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, not only cause localized oral diseases but can also have systemic implications. Porphyromonas gingivalis has been linked to gut dysbiosis, surviving stomach acid and disrupting the gut microbiome. Moreover, gingipain secreted by this bacterium has been implicated in the development of Alzheimer’s disease. Aggregatibacter actinomycetemcomitans, on the other hand, has been found to increase the metastatic potential of pancreatic cancer. The inflammatory response triggered by these bacteria, rather than their direct destruction, contributes to the breakdown of tooth-bearing tissues and feeds into systemic inflammation.
Osteoimmunology, the study of the interaction between the immune system and bone metabolism, provides insights into the complex relationship between inflammation and bone health. Bone, once considered relatively inert, is now recognized as a dynamic tissue undergoing constant remodeling. This process is regulated by various factors, including RANKL (receptor activator of nuclear factor kappa B ligand) and OPG (osteoprotegerin), which modulate osteoclast activity. Bacterial lipopolysaccharides, such as those from Porphyromonas gingivalis, have been shown to increase RANKL expression in osteoblasts, resulting in bone loss in periodontal disease.
Understanding these intricate connections between oral health, the microbiome, osteoimmunology, and systemic health is of utmost importance in biological dentistry. By considering the impact of oral pathogens and inflammation on systemic health, a comprehensive approach can be adopted to promote oral and overall well-being. Further research and clinical investigations are warranted to advance our understanding and develop effective strategies in biological dentistry to improve patient outcomes and systemic health.
Blood Tests to Determine the Impact of the Mouth on the Body
Blood Tests to Determine the Impact of the Mouth on the Body
Integrative medicine does not exist without biological dentistry. The mouth with teeth is part of the body that, with its inflammatory conditions and metallic materials, affects health.
At the same time, any body therapy cannot be effective if the body is burdened with oral conditions. Infections can lead to periodontitis or periodontal disease, “dead” teeth with granulomas, and among the metals, there is amalgam containing mercury, as well as most metallic alloys used in bridges and dentures. Inflammation creates an acidic environment, accelerating the “dissolution” of metals that deposit in the body.
In biological dentistry, thorough diagnostics are crucial, including oral examinations, even with a microscope, computer analysis of the periodontal disease status, X-rays, including CBCT, Dark Field microscopy, analysis of inflammatory mediators, etc.
When the diagnostics reveal what needs to be done, the therapeutic phase follows, in which we strictly follow protein-free and biocompatible trends. All materials are carefully selected and body-friendly. In surgery, we use techniques such as PRF, ozone, and PMP – pulsed magnetic field after procedures. These approaches allow us to avoid the use of antibiotics, significantly reducing complications and pain after procedures. In the field of dentures and bridges, we exclusively practice digital dentistry, which provides excellent precision and comfort. If you experience anxiety, we also offer inhalation sedation, “laughing gas,” to provide relaxation before and during procedures.
Blood Tests to Determine the Impact of the Mouth on the Body
- For those who have already been diagnosed with any condition and wish to understand its causes and eliminate them.
- For individuals who have experienced illness and are in the rehabilitation phase in one way or another.
- For those who perceive symptoms of imbalance but have not yet developed specific disease signs.
- For healthy individuals who want to strengthen their body and mind and maintain their well-being in the long run.
Biocompatible Implants - Zirconium Oxide
Biocompatible Implants - Zirconium Oxide
Loss of a tooth, resulting from disease or mechanical damage, not only affects an individual's aesthetic appearance but also significantly impacts the functionality of the bite. When we decide to get a dental implant, we probably envision a carefree life in the future.
We look forward to having all our teeth, but we often forget that inappropriate materials or execution can bring more problems than tooth loss itself. There are numerous metal implants available, and it is crucial to choose the right brand very carefully. However, it is a fact that the use of ceramic implants made of zirconia oxide is increasing. These ceramic implants are much better substitutes than their metal predecessors. Since they differ from each other, the brand used is also important. It has been proven that the oral mucosa has a high affinity for the surface of zirconia implants, leading to quality gum attachment at the implant interface. This fact is crucial in reducing inflammation around ceramic implants compared to metal implants. Inflammation around implants follows a similar pattern as inflammation in periodontal tissues and is caused by similar bacteria. Because tissue inflammation around implants progresses faster than with natural teeth, it is of utmost importance to prevent the occurrence of inflammation, among other things, by choosing the appropriate material from which the implant is made.
ACHIEVING LONG-TERM SATISFACTION WITH THE RIGHT PROCEDURE
The key to success with dental implants lies in the correct procedure—without haste and unrealistic promises. The first step is a thorough examination of the gums and a radiographic analysis and simulation of implant placement using a CBCT scan. In cases of gum disease, we must take our time to completely heal the gums. The therapist assesses whether there is sufficient bone and if the space is suitable for implant placement. If there is not enough bone, bone and gum grafting procedures follow, which must heal properly. Only after thorough preparation can the implant placement be performed. Imagine not knowing this and receiving a dental implant on diseased gums with insufficient bone for implant integration. In such cases, severe complications can arise, and often, such implants need to be removed. Therefore, it is essential to take the time for such a significant procedure and follow the prescribed protocols to be satisfied with the dental replacement that will serve as a permanent tooth. After all, we want to have it for a lifetime.
AESTHETICS – THE FINAL STEP TOWARDS SATISFACTION
Metal implants can cause the formation of a dark gum line around the implant, while zirconia implants have a more natural tone that seamlessly blends with the gum color. Even in cases of bone and tissue deficiency, the potential transparency of a dental implant due to its white color is much more favorable compared to a metal implant. The white color ensures a high aesthetic result, which is particularly important for replacing teeth in the front, visible area.
Therefore, ceramic implants represent an attractive upgrade to traditional metal solutions. Due to their numerous advantages, especially biocompatibility and a more natural appearance, they are increasingly being used. With further technological advancements and an increased awareness of the importance of the materials we implant in the body, ceramic implants will likely completely replace metal implants in the future.
Dead Teeth - Granulomas
Dead Teeth - Granulomas
Dead teeth are a result of granulomas and can be extremely harmful if not properly treated. Similar to periodontal disease, we are dealing with highly aggressive bacteria here, which lead to the decay of tissues inside the tooth, specifically the dental pulp or nerve.
The process begins when bacteria reach the inside of the tooth through a cavity or tooth decay, triggering an immune response. Teeth are hard structures, and the swelling that always occurs in response to an infection cannot expand, resulting in compression of the blood vessels and “suffocation” of the tooth, accelerating the death of the nerve. Once the dental nerve dies throughout the root canal, bacteria reach the bone in the lower or upper jaw. Here, an immune response called a granuloma or chronic periapical periodontitis can develop. The bacteria do not freely pass through the bone they reached through the tooth; instead, a so-called “front” is formed. On one side, bacteria penetrate deeper into the bone with their secretions, while on the other side, the immune response attempts to contain it. Since the influx of bacteria from inside the tooth is continuous, and they actually have a good hiding place and rear base, the immune system cannot heal the granuloma. Eventually, an untreated tooth will inevitably be lost. As long as it is still present, the bone progressively disappears. If periodontal disease is also present, the processes can merge, resulting in the tooth losing its bone support. Since the bacteria involved in both processes are very similar, the impact on the body is also similar.
Such teeth are extremely harmful to the body, so the examination and treatment should be approached accordingly.
It is possible to infer whether you have such a tooth present in your mouth. It should be noted that many oral conditions do not manifest as painful sensations or discomfort. Approximately 80% of granulomas are discovered as part of routine examinations.
The most common warning sign of this type of condition is undefined or nonspecific pain that does not occur continuously. You often complain of having caught a cold in your jaw, feeling a strange sensation for several days after sailing, hiking, and similar activities. This is a clear warning that there may be a granuloma in the jawbone and that urgent action is required.
Granulomas pose a significant risk to overall health.
It is much better to perform granuloma treatment procedures when the body is in good condition and before severe symptoms such as pain, swelling, or tooth mobility occur. At that time, the chances of successful treatment are increased by 20-25%, and the long-term prognosis for tooth retention in the mouth is good. Of course, this applies while considering and adhering to all modern guidelines for root canal treatment. The mandatory use of an operating microscope, proper isolation of the tooth to ensure clean working conditions, bioactive fillings, and sufficient time for the procedure are essential. Such procedures are not typically performed under time pressure. Only after a one-year follow-up X-ray evaluation can we assess whether the granuloma has healed. Only then can we consider the treatment of the tooth as successful. If treatment is not successful, additional surgical procedures may be necessary, or we may discuss the extraction of such a tooth.
Today, there are great possibilities for the proper management of dead teeth, using the latest materials and technologies, along with the importance of a well-trained therapist. Properly managed and radiographically monitored dead teeth are much better than implants.
The problem lies in teeth that have not been optimally treated.
There are many such teeth in the mouth worldwide. It is important to emphasize that this is not due to the negligence or lack of knowledge of dentists but rather because advanced technology, materials, and knowledge in this field were not available in the past.
If the tooth is well
treated, and the root canal system is thoroughly cleaned, it can be as good as a regular tooth that still has the dental nerve.
But what about teeth that are not fully treated?
Such teeth are a severe problem and need to be extracted. Treated dead teeth should be regularly monitored with X-rays. If the X-ray shows that the bone has healed, then that tooth is definitely harmless to your body. If the bone has not healed, we have two options. The first is a so-called microscopic apicoectomy, in which we use a microscope to remove the unhealed granuloma from the body by also removing the lower part of the root. The second option is tooth extraction.
Amalgam and Other Alloys in the Mouth
Amalgam and Other Alloys in the Mouth
Silver or amalgam fillings contain 50 percent mercury, which has been scientifically proven to be more toxic than lead, cadmium, or arsenic. Amalgam fillings can potentially have neurotoxic effects. Some healthcare experts believe that mercury causes physical and psychological problems and directly affects most brain functions.
Mercury can enter the body in several ways. Small particles of amalgam from the filling, which dissolve in saliva, can be swallowed and then absorbed into the bloodstream and nerves through the intestines. A certain percentage of mercury vaporizes from the fillings and is absorbed into the lungs through inhalation. Mercury can also directly penetrate the tooth and, through the dental nerve, travel along other nerves to the brain, where it is stored. There is also a possibility that mercury starts to leak from the amalgam filling and gradually penetrates organs in small quantities. The body deposits them in tissues and organs, causing various physical and psychological problems and illnesses.
Given all of the above, there are at least 5 good reasons to replace amalgam fillings with composite white fillings or porcelain or composite inlays:
1. HYGIENE: Amalgam fillings contract more than the tooth in cold temperatures. Over time, gaps form between the filling and the tooth, where bacteria settle and cannot be removed even with meticulous oral hygiene.
2. TOOTH DAMAGE: Amalgam fillings expand more than the tooth when consuming hot food and drinks. This creates tension in the tooth and can lead to cracks, which may result in tooth loss.
3. MERCURY: Amalgam contains toxic mercury, which is proven to be harmful to our bodies. More and more experts believe that mercury causes physical and psychological issues and directly affects most brain functions.
4. GALVANIC REACTIONS: The presence of amalgam fillings and/or other metals in the mouth leads to the generation of low-voltage electrical currents, causing the well-known “metallic sensation” in the mouth.
5. AESTHETICS: An increasing number of people find amalgam fillings unattractive due to their gray appearance. They desire a wide, relaxed, and white smile.
Periodontal Disease and the Body
Periodontal Disease and the Body
Despite periodontal disease affecting as many as 80% of Slovenian men and women, we still underestimate the extent of this pathological condition.
